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The role of transient hypermutators in adaptive mutation in Escherichia coli

Microbial populations under nonlethal selection can give rise to mutations that relieve the selective pressure, a phenomenon that has come to be called “adaptive mutation.” One explanation for adaptive mutation is that a small proportion of the cells experience a period of transient hypermutation, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rosche, William A., Foster, Patricia L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22007/
https://ncbi.nlm.nih.gov/pubmed/10359804
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