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Retroviral mutation rates and A-to-G hypermutations during different stages of retroviral replication.

Retroviruses mutate at a high rate in vivo during viral replication. Mutations may occur during proviral transcription by RNA polymerase II, during minus-strand DNA synthesis (RNA template) by viral reverse transcriptase, or during plus-strand DNA synthesis (DNA template) by reverse transcriptase. T...

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Detalhes bibliográficos
Main Authors: Kim, T, Mudry, R A, Rexrode, C A, Pathak, V K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190828/
https://ncbi.nlm.nih.gov/pubmed/8892879
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