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Continuous targeted hypermutation with a tunable mutation window

Abstract Targeted in vivo hypermutation drives rapid sequence diversification within specific DNA regions of living cells, enabling continuous evolution of biomolecules for enhanced functionality. In living organisms, this is prominently illustrated by the preferential somatic hypermutation of compl...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chanwoo Lee, Seokhee Kim
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-11-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-025-66736-2
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