Continuous targeted hypermutation with a tunable mutation window
Abstract Targeted in vivo hypermutation drives rapid sequence diversification within specific DNA regions of living cells, enabling continuous evolution of biomolecules for enhanced functionality. In living organisms, this is prominently illustrated by the preferential somatic hypermutation of compl...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2025-11-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-025-66736-2 |
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