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[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism
[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) (antagonist G) is a novel class of anti-cancer agent that inhibits small-cell lung cancer (SCLC) cell growth in vitro and in vivo and is entering phase II clinical investigation for the treatment of SCLC. Although antagonist G blocks SCLC cell growt...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363053/ https://ncbi.nlm.nih.gov/pubmed/10362111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690458 |
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