Mutation testing in melanoma families: INK4A, CDK4 and INK4D

The INK4A gene which codes for the cyclin-dependent kinase (CDK) inhibitor INK4A or p16 underlies susceptibility to melanoma in some families. Germline mutations in the gene that codes for the target protein of p16, CDK4, underlie susceptibility in very rare families. We report mutation screening of...

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書誌詳細
主要な著者: Newton Bishop, J A, Harland, M, Bennett, D C, Bataille, V, Goldstein, A M, Tucker, M A, Ponder, B A J, Cuzick, J, Selby, P, Bishop, D T
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1999
主題:
Regular Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363010/
https://ncbi.nlm.nih.gov/pubmed/10390011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690354
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