Mutation testing in melanoma families: INK4A, CDK4 and INK4D

The INK4A gene which codes for the cyclin-dependent kinase (CDK) inhibitor INK4A or p16 underlies susceptibility to melanoma in some families. Germline mutations in the gene that codes for the target protein of p16, CDK4, underlie susceptibility in very rare families. We report mutation screening of...

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Detalhes bibliográficos
Main Authors: Newton Bishop, J A, Harland, M, Bennett, D C, Bataille, V, Goldstein, A M, Tucker, M A, Ponder, B A J, Cuzick, J, Selby, P, Bishop, D T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363010/
https://ncbi.nlm.nih.gov/pubmed/10390011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690354
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