A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil

The prognostic value of tumoural epidermal growth factor receptor (EGFR), p53, thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) was analysed on 82 advanced head and neck cancer patients (71 men, 11 women; mean age 59). Induction treatment was cisplatin–5-FU ± folinic acid (61 pati...

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Detalhes bibliográficos
Main Authors: Etienne, M C, Pivot, X, Formento, J L, Bensadoun, R J, Formento, P, Dassonville, O, Francoual, M, Poissonnet, G, Fontana, X, Schneider, M, Demard, F, Milano, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362780/
https://ncbi.nlm.nih.gov/pubmed/10206306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690297
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