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Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme of 5-fluorouracil (5-FU) catabolism. We report lymphocytic DPD data concerning a group of 53 patients (23 men, 30 women, mean age 58, range 36–73), treated by 5-FU-based chemotherapy in different French institutions and wh...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362417/ https://ncbi.nlm.nih.gov/pubmed/10027340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690098 |
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