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Increased expression of the RIα subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer

The primary element in the cAMP signal transduction pathway is the cAMP-dependent protein kinase (PKA). Expression of the RIα subunit of type I PKA is elevated in a variety of human tumours and cancer cell lines. The purpose of this study was to assess the prognostic importance of RIα expression in...

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Detalhes bibliográficos
Main Authors: McDaid, H M, Cairns, M T, Atkinson, R J, McAleer, S, Harkin, D P, Gilmore, P, Johnston, P G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362667/
https://ncbi.nlm.nih.gov/pubmed/10070893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690149
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