In Vitro Culture During Retroviral Transduction Improves Thymic Repopulation and Output After Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation in Rhesus Macaques

Immunodeficiency after peripheral blood progenitor cell (PBPC) transplantation may be influenced by graft composition, underlying disease, and/or pre-treatment. These factors are difficult to study independently in humans. Ex vivo culture and genetic manipulation of PBPC grafts may also affect immun...

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Autori principali: Loré, Karin, Seggewiss, Ruth, Guenaga, F. Javier, Pittaluga, Stefania, Donahue, Robert E., Krouse, Allen, Metzger, Mark E., Koup, Richard A., Reilly, Cavan, Douek, Daniel C., Dunbar, Cynthia E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362389/
https://ncbi.nlm.nih.gov/pubmed/16497945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2005-0455
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