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Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase
DT-diaphorase is a two-electron reducing enzyme that activates the bioreductive anti-tumour agent, mitomycin C (MMC). Cell lines having elevated levels of DT-diaphorase are generally more sensitive to MMC. We have shown that DT-diaphorase can be induced in human tumour cells by a number of compounds...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
1999
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362377/ https://ncbi.nlm.nih.gov/pubmed/10376975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690489 |
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