Chargement en cours...

Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase

DT-diaphorase is a two-electron reducing enzyme that activates the bioreductive anti-tumour agent, mitomycin C (MMC). Cell lines having elevated levels of DT-diaphorase are generally more sensitive to MMC. We have shown that DT-diaphorase can be induced in human tumour cells by a number of compounds...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, X, Doherty, G P, Leith, M K, Curphey, T J, Begleiter, A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362377/
https://ncbi.nlm.nih.gov/pubmed/10376975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690489
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!