Selective inhibition of TNF-α-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib

We have reported that the selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, gefitinib (‘Iressa’, ZD1839), suppressed intrahepatic metastasis of hepatocellular carcinoma CBO140C12 cells. In this study, we focused on the tumour necrosis factor-α (TNF-α) signalling pathways....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ueno, Y, Sakurai, H, Matsuo, M, Choo, M K, Koizumi, K, Saiki, I
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Translational Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362047/
https://ncbi.nlm.nih.gov/pubmed/15841081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602548
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