Selective inhibition of TNF-α-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib

We have reported that the selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, gefitinib (‘Iressa’, ZD1839), suppressed intrahepatic metastasis of hepatocellular carcinoma CBO140C12 cells. In this study, we focused on the tumour necrosis factor-α (TNF-α) signalling pathways....

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Detalhes bibliográficos
Main Authors: Ueno, Y, Sakurai, H, Matsuo, M, Choo, M K, Koizumi, K, Saiki, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362047/
https://ncbi.nlm.nih.gov/pubmed/15841081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602548
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