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Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
Hypoxia is a key factor contributing to the progression of human neoplasias and to the development of resistance to chemotherapy. BNIP3 is a proapoptotic member of the Bcl-2 protein family involved in hypoxia-induced cell death. We evaluated the expression and methylation status of BNIP3 gene to bet...
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| Hlavní autoři: | , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361956/ https://ncbi.nlm.nih.gov/pubmed/15756280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602422 |
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