Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines

Transcription factor 2 gene (TCF2) encodes hepatocyte nuclear factor 1β (HNF1β), a transcription factor associated with development and metabolism. Mutation of TCF2 has been observed in renal cell cancer, and by screening aberrantly methylated genes, we have now identified TCF2 as a target for epige...

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Autores principales: Terasawa, K, Toyota, M, Sagae, S, Ogi, K, Suzuki, H, Sonoda, T, Akino, K, Maruyama, R, Nishikawa, N, Imai, K, Shinomura, Y, Saito, T, Tokino, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2006
Materias:
Genetics and Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361363/
https://ncbi.nlm.nih.gov/pubmed/16479257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602984
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