Epigenetic inactivation of CHFR in human tumors

Cell-cycle checkpoints controlling the orderly progression through mitosis are frequently disrupted in human cancers. One such checkpoint, entry into metaphase, is regulated by the CHFR gene encoding a protein possessing forkhead-associated and RING finger domains as well as ubiquitin–ligase activit...

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Autors principals: Toyota, Minoru, Sasaki, Yasushi, Satoh, Ayumi, Ogi, Kazuhiro, Kikuchi, Takefumi, Suzuki, Hiromu, Mita, Hiroaki, Tanaka, Nobuyuki, Itoh, Fumio, Issa, Jean-Pierre J., Jair, Kam-Wing, Schuebel, Kornel E., Imai, Kohzoh, Tokino, Takashi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC164671/
https://ncbi.nlm.nih.gov/pubmed/12810945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1337066100
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