DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers

Death-associated protein kinase is a positive regulator of programmed cell death induced by interferon γ. To investigate the role of epigenetic inactivation of death-associated protein kinase in gastrointestinal cancer, we examined the methylation status of the 5′ CpG island of the death-associated...

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Detalhes bibliográficos
Main Authors: Satoh, A, Toyota, M, Itoh, F, Kikuchi, T, Obata, T, Sasaki, Y, Suzuki, H, Yawata, A, Kusano, M, Fujita, M, Hosokawa, M, Yanagihara, K, Tokino, T, Imai, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375414/
https://ncbi.nlm.nih.gov/pubmed/12087472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600319
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