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Combined effects of GSTP1 and MRP1 in melanoma drug resistance

Glutathione-S-transferase Pi1 (GSTP1) and multidrug resistance protein 1 (MRP1) are overexpressed in melanoma, a skin cancer notoriously resistant to all current modalities of cancer therapy. To investigate the involvement of these detoxifying enzymes in the drug resistance of melanoma, an inducible...

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Autori principali: Depeille, P, Cuq, P, Passagne, I, Evrard, A, Vian, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361556/
https://ncbi.nlm.nih.gov/pubmed/15999103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602681
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