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Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer

Activation of kinases signalling pathways contributes to various malignant phenotypes in human cancers, including breast tumour. To examine the possible activation of these signalling molecules, we examined the phosphorylation status in 12 protein kinases and transcription factors in normal primary...

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Autors principals: Lin, H-J, Hsieh, F-C, Song, H, Lin, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361529/
https://ncbi.nlm.nih.gov/pubmed/16288304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602862
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