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Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway

BACKGROUND: A major therapeutic challenge for breast cancer is the ability of cancer cells to evade killing of conventional chemotherapeutic agents. We have recently reported the actin-bundling protein (fascin) as a major regulator of breast cancer metastasis and survival. METHODS: Survival of breas...

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Bibliografske podrobnosti
Main Authors:	Ghebeh, H, Al-Khaldi, S, Olabi, S, Al-Dhfyan, A, Al-Mohanna, F, Barnawi, R, Tulbah, A, Al-Tweigeri, T, Ajarim, D, Al-Alwan, M
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2014
Teme:	Translational Therapeutics
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4200093/ https://ncbi.nlm.nih.gov/pubmed/25117814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.453
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Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway

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