Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridisation

The initiating somatic genetic events in chordoma development have not yet been identified. Most cytogenetically investigated chordomas have displayed near-diploid or moderately hypodiploid karyotypes, with several numerical and structural rearrangements. However, no consistent structural chromosome...

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Autores principales: Hallor, K H, Staaf, J, Jönsson, G, Heidenblad, M, Vult von Steyern, F, Bauer, H C F, IJszenga, M, Hogendoorn, P C W, Mandahl, N, Szuhai, K, Mertens, F
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361468/
https://ncbi.nlm.nih.gov/pubmed/18071362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604130
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