Genomic Aberrations Frequently Alter Chromatin Regulatory Genes in Chordoma

Chordoma is a rare primary bone neoplasm that is resistant to standard chemotherapies. Despite aggressive surgical management, local recurrence and metastasis is not uncommon. To identify the specific genetic aberrations that play key roles in chordoma pathogenesis, we utilized a genome-wide high-re...

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Wang, Lu, Zehir, Ahmet, Nafa, Khedoudja, Zhou, Nengyi, Berger, Michael F., Casanova, Jacklyn, Sadowska, Justyna, Lu, Chao, Allis, C. David, Gounder, Mrinal, Chandhanayingyong, Chandhanarat, Ladanyi, Marc, Boland, Patrick J, Hameed, Meera
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031498/
https://ncbi.nlm.nih.gov/pubmed/27072194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22362
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