Genomic Aberrations Frequently Alter Chromatin Regulatory Genes in Chordoma

Chordoma is a rare primary bone neoplasm that is resistant to standard chemotherapies. Despite aggressive surgical management, local recurrence and metastasis is not uncommon. To identify the specific genetic aberrations that play key roles in chordoma pathogenesis, we utilized a genome-wide high-re...

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Bibliografiske detaljer
Udgivet i:Genes Chromosomes Cancer
Main Authors: Wang, Lu, Zehir, Ahmet, Nafa, Khedoudja, Zhou, Nengyi, Berger, Michael F., Casanova, Jacklyn, Sadowska, Justyna, Lu, Chao, Allis, C. David, Gounder, Mrinal, Chandhanayingyong, Chandhanarat, Ladanyi, Marc, Boland, Patrick J, Hameed, Meera
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031498/
https://ncbi.nlm.nih.gov/pubmed/27072194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22362
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