Genomic Aberrations Frequently Alter Chromatin Regulatory Genes in Chordoma

Chordoma is a rare primary bone neoplasm that is resistant to standard chemotherapies. Despite aggressive surgical management, local recurrence and metastasis is not uncommon. To identify the specific genetic aberrations that play key roles in chordoma pathogenesis, we utilized a genome-wide high-re...

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Библиографические подробности
Опубликовано в: :Genes Chromosomes Cancer
Главные авторы: Wang, Lu, Zehir, Ahmet, Nafa, Khedoudja, Zhou, Nengyi, Berger, Michael F., Casanova, Jacklyn, Sadowska, Justyna, Lu, Chao, Allis, C. David, Gounder, Mrinal, Chandhanayingyong, Chandhanarat, Ladanyi, Marc, Boland, Patrick J, Hameed, Meera
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031498/
https://ncbi.nlm.nih.gov/pubmed/27072194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22362
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