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Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma
Overexpression of the transcriptional activator β-catenin, mostly owing to loss-of-function mutations of the adenomatous polyposis coli (APC) tumour suppressor gene, is crucial for the initiation and progression of human colorectal carcinogenesis. Securin is a regulator of chromosome separation and...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361298/ https://ncbi.nlm.nih.gov/pubmed/16705313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603155 |
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