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A selective retinoid X receptor agonist bexarotene (LGD1069, targretin) inhibits angiogenesis and metastasis in solid tumours

The present study determined the influence of a retinoid X receptor agonist bexarotene on angiogenesis and metastasis in solid tumours. In the experimental lung metastasis xenograft models, treatment with bexarotene inhibited the development of the lung tumour nodule formation compared to control. I...

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Bibliografiske detaljer
Main Authors: Yen, W-C, Prudente, R Y, Corpuz, M R, Negro-Vilar, A, Lamph, W W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361207/
https://ncbi.nlm.nih.gov/pubmed/16495926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602995
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