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The Retinoid Agonist Tazarotene Promotes Angiogenesis and Wound Healing

Therapeutic angiogenesis is a major goal of regenerative medicine, but no clinically approved small molecule exists that enhances new blood vessel formation. Here we show, using a phenotype-driven high-content imaging screen of an annotated chemical library of 1,280 bioactive small molecules, that t...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Al Haj Zen, Ayman, Nawrot, Dorota A, Howarth, Alison, Caporali, Andrea, Ebner, Daniel, Vernet, Aude, Schneider, Jurgen E, Bhattacharya, Shoumo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112045/
https://ncbi.nlm.nih.gov/pubmed/27480772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.153
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