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mTOR signaling: implications for cancer and anticancer therapy
Mounting evidence links deregulated protein synthesis to tumorigenesis via the translation initiation factor complex eIF4F. Components of this complex are often overexpressed in a large number of cancers and promote malignant transformation in experimental systems. mTOR affects the activity of the e...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361102/ https://ncbi.nlm.nih.gov/pubmed/16404421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602902 |
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