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Clinical and laboratory experience of vorinostat (suberoylanilide hydroxamic acid) in the treatment of cutaneous T-cell lymphoma

The most common cutaneous T-cell lymphomas (CTCLs) – mycosis fungoides (MF) and Sézary Syndrome – are characterised by the presence of clonally expanded, skin-homing helper-memory T cells exhibiting abnormal apoptotic control mechanisms. Epigenetic modulation of genes that induce apoptosis and diffe...

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Autori principali: Duvic, M, Zhang, C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360772/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603465
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