Thymidylate synthase polymorphisms, folate and B-vitamin intake, and risk of colorectal adenoma

The effects of polymorphisms in genes coding for key folate metabolism enzymes such as thymidylate synthetase (TS) on colorectal neoplasia risk are likely to be influenced by gene–gene and gene–nutrient interactions. We investigated the combined effects of three polymorphisms in the TS gene region,...

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Bibliographic Details
Main Authors: Hubner, R A, Liu, J-F, Sellick, G S, Logan, R F A, Houlston, R S, Muir, K R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360236/
https://ncbi.nlm.nih.gov/pubmed/17971770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604056
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