Prognostic significance of folate metabolism polymorphisms for lung cancer

Functional nonsynonymous single-nucleotide polymorphisms (nsSNPs) of folate metabolism genes can influence the methylation of tumour suppressor genes, thereby potentially impacting on tumour behaviour. To investigate whether such polymorphisms influence lung cancer survival, we genotyped 14 nsSNPs m...

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Bibliografiske detaljer
Main Authors: Matakidou, A, el Galta, R, Rudd, M F, Webb, E L, Bridle, H, Eisen, T, Houlston, R S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360297/
https://ncbi.nlm.nih.gov/pubmed/17533396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603830
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