Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice

Cardiac damage is the major limiting factor for the clinical use of doxorubicin (DOX). Preclinical studies indicate that inflammatory effects may be involved in DOX-induced cardiotoxicity. N(ε)-(carboxymethyl) lysine (CML) is suggested to be generated subsequent to oxidative stress, including inflam...

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Main Authors: Bruynzeel, A M E, Abou El Hassan, M A, Schalkwijk, C, Berkhof, J, Bast, A, Niessen, H W M, van der Vijgh, W J F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Translational Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360105/
https://ncbi.nlm.nih.gov/pubmed/17325706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603640
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