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Caspase-dependent and -independent suppression of apoptosis by monoHER in Doxorubicin treated cells

Doxorubicin (DOX) is an antitumour agent for different types of cancer, but the dose-related cardiotoxicity limits its clinical use. To prevent this side effect we have developed the flavonoid monohydroxyethylrutoside (monoHER), a promising protective agent, which did not interfere with the antitumo...

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Detalhes bibliográficos
Main Authors: Bruynzeel, A M E, Abou El Hassan, M A, Torun, E, Bast, A, van der Vijgh, W J F, Kruyt, F A E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360019/
https://ncbi.nlm.nih.gov/pubmed/17285121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603598
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