Llwytho...

A comparative study between catalase gene therapy and the cardioprotector monohydroxyethylrutoside (MonoHER) in protecting against doxorubicin-induced cardiotoxicity in vitro

Cardiotoxicity is the main dose-limiting side effect of doxorubicin in the clinic. Being a free radical producer, doxorubicin affects the heart specifically because of its low antioxidant capacity. Among those antioxidants, catalase is present in very low levels in the heart compared to other organs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abou El Hassan, M A I, Rabelink, M J W E, van der Vijgh, W J F, Bast, A, Hoeben, R C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376857/
https://ncbi.nlm.nih.gov/pubmed/14647150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601430
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