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The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals
Scar formation occurs during the late stages of the inflammatory response but, when excessive, produces fibrosis that can lead to functional and structural damage of tissues. Here, we show that the profibrogenic agonist, transforming growth factor β1, transcriptionally decreases expression of Exchan...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359804/ https://ncbi.nlm.nih.gov/pubmed/18434542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801490105 |
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