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Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini

The pancreatic acinar cell has several phenotypic responses to cAMP agonists. At physiological concentrations of the muscarinic agonist carbachol (1 μM) or the CCK analog caerulein (100 pM), ligands that increase cytosolic Ca(2+), cAMP acts synergistically to enhance secretion. Supraphysiological co...

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Bibliografische gegevens
Hoofdauteurs: Chaudhuri, Anamika, Husain, Sohail Z., Kolodecik, Thomas R., Grant, Wayne M., Gorelick, Fred S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975017/
https://ncbi.nlm.nih.gov/pubmed/17234888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00478.2005
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