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The ryanodine receptor mediates early zymogen activation in pancreatitis
Acute pancreatitis is characterized by the pathologic activation of zymogens within pancreatic acinar cells. The process requires a rise in cytosolic Ca(2+) from undefined intracellular stores. We hypothesized that zymogen activation is mediated by ryanodine receptor (RYR)-regulated Ca(2+) release,...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242288/ https://ncbi.nlm.nih.gov/pubmed/16186498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503215102 |
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