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Alcohols enhance caerulein-induced zymogen activation in pancreatic acinar cells

Activation of zymogens within the pancreatic acinar cell is an early feature of acute pancreatitis. Supraphysiological concentrations of cholecystokinin (CCK) cause zymogen activation and pancreatitis. The effects of the CCK analog, caerulein, and alcohol on trypsin and chymotrypsin activation in is...

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Detalhes bibliográficos
Main Authors: LU, ZHAO, KARNE, SURESH, KOLODECIK, THOMAS, GORELICK, FRED S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830557/
https://ncbi.nlm.nih.gov/pubmed/11842000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00388.2001
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