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The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone

The Gram-negative bacterium Pseudomonas aeruginosa, an opportunistic human pathogen, uses acylhomoserine lactone-based quorum sensing systems to control its pathogenicity. One of its quorum sensing factors, N-3-oxo-dodecanoyl homoserine lactone, has been shown not only to mediate bacterial quorum se...

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Bibliografische gegevens
Hoofdauteurs: Kaufmann, Gunnar F., Park, Junguk, Mee, Jenny M., Ulevitch, Richard J., Janda, Kim D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359578/
https://ncbi.nlm.nih.gov/pubmed/18304641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.01.010
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