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Bacterial Quorum Sensing Molecule N-3-Oxo-Dodecanoyl-L-Homoserine Lactone Causes Direct Cytotoxicity and Reduced Cell Motility in Human Pancreatic Carcinoma Cells

In spite of chemotherapeutic and surgical advances, pancreatic cancer continues to have a dismal prognosis. Metastasis due to tumor cell migration remains the most critical challenge in treating pancreatic cancer, and conventional chemotherapy is rarely curative. In the quest for more novel molecule...

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Autori principali: Kumar, Ashwath S., Bryan, Jeffrey N., Kumar, Senthil R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154711/
https://ncbi.nlm.nih.gov/pubmed/25188245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106480
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