Quorum Quenching by an N-Acyl-Homoserine Lactone Acylase from Pseudomonas aeruginosa PAO1

The virulence of the opportunistic human pathogen Pseudomonas aeruginosa PAO1 is controlled by an N-acyl-homoserine lactone (AHL)-dependent quorum-sensing system. During functional analysis of putative acylase genes in the P. aeruginosa PAO1 genome, the PA2385 gene was found to encode an acylase tha...

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Hlavní autoři: Sio, Charles F., Otten, Linda G., Cool, Robbert H., Diggle, Stephen P., Braun, Peter G., Bos, Rein, Daykin, Mavis, Cámara, Miguel, Williams, Paul, Quax, Wim J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418629/
https://ncbi.nlm.nih.gov/pubmed/16495538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.3.1673-1682.2006
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