Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator
cAMP-dependent phosphorylation activates the cystic fibrosis transmembrane conductance regulator (CFTR) in epithelia. However, the protein phosphatase (PP) that dephosphorylates and inactivates CFTR in airway and intestinal epithelia, two major sites of disease, is not certain. We found that in airw...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1997
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.11055 |
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