Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator

cAMP-dependent phosphorylation activates the cystic fibrosis transmembrane conductance regulator (CFTR) in epithelia. However, the protein phosphatase (PP) that dephosphorylates and inactivates CFTR in airway and intestinal epithelia, two major sites of disease, is not certain. We found that in airw...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Travis, Sue M., Berger, Herbert A., Welsh, Michael J.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1997
Gaiak:	Biological Sciences
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9380758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.20.11055
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