A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution

Phosphorylation of the regulatory (R) domain initiates cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel activity. To discover how the function of this domain is determined by its structure, we produced an R domain protein (R8) that spanned residues 708–831 of CFTR. Phosphoryl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ostedgaard, Lynda S., Baldursson, Olafur, Vermeer, Daniel W., Welsh, Michael J., Robertson, Andrew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25884/
https://ncbi.nlm.nih.gov/pubmed/10792060
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky