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Down-regulation of interferon γ-activated STAT1 by UV light

STAT1 is a cytoplasmic transcription factor that is phosphorylated by Janus kinases (Jak) in response to interferon-γ (IFNγ). Phosphorylated STAT1 translocates to the nucleus, where it turns on specific sets of IFNγ-inducible genes. Here, we show that UV light interferes with tyrosine phosphorylatio...

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Detalles Bibliográficos
Main Authors: Aragane, Yoshinori, Kulms, Dagmar, Luger, Thomas A., Schwarz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC23515/
https://ncbi.nlm.nih.gov/pubmed/9326637
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