Interferon-γ links UV to melanocyte activation and promotes melanomagenesis

Cutaneous malignant melanoma is a highly aggressive and frequently chemoresistant cancer, whose incidence continues to rise. Epidemiological studies reveal that the major etiological melanoma risk factor is ultraviolet (UV) solar radiation, with the highest risk associated with intermittent burning...

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Main Authors: Zaidi, M. Raza, Davis, Sean, Noonan, Frances P., Graff-Cherry, Cari, Hawley, Teresa S., Walker, Robert L., Feigenbaum, Lionel, Fuchs, Elaine, Lyakh, Lyudmila, Young, Howard A., Hornyak, Thomas J., Arnheiter, Heinz, Trinchieri, Giorgio, Meltzer, Paul S., De Fabo, Edward C., Merlino, Glenn
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140101/
https://ncbi.nlm.nih.gov/pubmed/21248750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09666
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