Interferon-γ links UV to melanocyte activation and promotes melanomagenesis

Cutaneous malignant melanoma is a highly aggressive and frequently chemoresistant cancer, whose incidence continues to rise. Epidemiological studies reveal that the major etiological melanoma risk factor is ultraviolet (UV) solar radiation, with the highest risk associated with intermittent burning...

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Detalhes bibliográficos
Main Authors: Zaidi, M. Raza, Davis, Sean, Noonan, Frances P., Graff-Cherry, Cari, Hawley, Teresa S., Walker, Robert L., Feigenbaum, Lionel, Fuchs, Elaine, Lyakh, Lyudmila, Young, Howard A., Hornyak, Thomas J., Arnheiter, Heinz, Trinchieri, Giorgio, Meltzer, Paul S., De Fabo, Edward C., Merlino, Glenn
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140101/
https://ncbi.nlm.nih.gov/pubmed/21248750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09666
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