Interferon-γ links UV to melanocyte activation and promotes melanomagenesis

Cutaneous malignant melanoma is a highly aggressive and frequently chemoresistant cancer, whose incidence continues to rise. Epidemiological studies reveal that the major etiological melanoma risk factor is ultraviolet (UV) solar radiation, with the highest risk associated with intermittent burning...

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Autors principals: Zaidi, M. Raza, Davis, Sean, Noonan, Frances P., Graff-Cherry, Cari, Hawley, Teresa S., Walker, Robert L., Feigenbaum, Lionel, Fuchs, Elaine, Lyakh, Lyudmila, Young, Howard A., Hornyak, Thomas J., Arnheiter, Heinz, Trinchieri, Giorgio, Meltzer, Paul S., De Fabo, Edward C., Merlino, Glenn
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140101/
https://ncbi.nlm.nih.gov/pubmed/21248750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09666
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