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Functional association between promoter structure and transcript alternative splicing

It has been assumed that constitutive and regulated splicing of RNA polymerase II transcripts depends exclusively on signals present in the RNA molecule. Here we show that changes in promoter structure strongly affect splice site selection. We investigated the splicing of the ED I exon, which encode...

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Autors principals: Cramer, Paula, Pesce, C. Gustavo, Baralle, Francisco E., Kornblihtt, Alberto R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23504/
https://ncbi.nlm.nih.gov/pubmed/9326631
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