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Functional association between promoter structure and transcript alternative splicing

It has been assumed that constitutive and regulated splicing of RNA polymerase II transcripts depends exclusively on signals present in the RNA molecule. Here we show that changes in promoter structure strongly affect splice site selection. We investigated the splicing of the ED I exon, which encode...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cramer, Paula, Pesce, C. Gustavo, Baralle, Francisco E., Kornblihtt, Alberto R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23504/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11456
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